Blar i NIVA Open Access Archive på forfatter "Burden, Natalie"

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    • Big Question to Developing Solutions: A Decade of Progress in the Development of Aquatic New Approach Methodologies from 2012 to 2022 

      Langan, Laura M.; Paparella, Martin; Burden, Natalie; Constantine, Lisa; Margiotta-Casaluci, Luigi; Miller, Thomas H.; Moe, S. Jannicke; Owen, Stewart F.; Schaffert, Alexandra; Sikanen, Tiina (Peer reviewed; Journal article, 2023)
      In 2012, 20 key questions related to hazard and exposure assessment and environmental and health risks of pharmaceuticals and personal care products in the natural environment were identified. A decade later, this article ...

    • Dying for change: A roadmap to refine the fish acute toxicity test after 40 years of applying a lethal endpoint 

      Katsiadaki, Ioanna; Ellis, Tim; Andersen, Linda; Antczak, Philipp; Blaker, Ellen; Burden, Natalie; Fisher, Tom; Green, Christopher; Labram, Briony; Pearson, Audrey; Petersen, Karina; Pickford, Dan; Ramsden, Chris; Rønneseth, Anita; Ryder, Kathy; Sacker, Dominic; Stevens, Chloe; Watanabe, Haruna; Yamamoto, Hiroshi; Sewell, Fiona; Hawkins, Penny; Rufli, Hans; Handy, Richard D.; Maynard, Samuel K.; Jacobs, Miriam (Peer reviewed; Journal article, 2021)
      The fish acute toxicity test (TG203; OECD, 2019) is frequently used and highly embedded in hazard and risk assessment globally. The test estimates the concentration of a chemical that kills 50% of the fish (LC50) over a ...

    • New Approach Methodologies for the Endocrine Activity Toolbox: Environmental Assessment for Fish and Amphibians 

      Mitchell, Constance A.; Burden, Natalie; Bonnell, Mark; Hecker, Markus; Hutchinson, Thomas H.; Jagla, Magdalena; LaLone, Carlie A.; Lagadic, Laurent; Lynn, Scott G.; Shore, Bryon; Song, You; Vliet, Sara M.; Wheeler, James R.; Embry, Michelle R. (Peer reviewed; Journal article, 2023)
      Multiple in vivo test guidelines focusing on the estrogen, androgen, thyroid, and steroidogenesis pathways have been developed and validated for mammals, amphibians, or fish. However, these tests are resource-intensive and ...